Broflanilide

CAS No. 1207727-04-5

Broflanilide ( —— )

Catalog No. M26075 CAS No. 1207727-04-5

Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR with IC50 of 1.3 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 66 Get Quote
5MG 110 Get Quote
10MG 178 Get Quote
25MG 390 Get Quote
50MG 593 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
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Biological Information

  • Product Name
    Broflanilide
  • Note
    Research use only, not for human use.
  • Brief Description
    Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR with IC50 of 1.3 nM.
  • Description
    Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR with IC50 of 1.3 nM.(In Vitro):Broflanilide is an insecticide and metabolized to desmethyl-broflanilide. Desmethyl-broflanilide shows weak activity against human GABAA α1β2γ2 receptor, the mammalian GABAA α1β3γ2 receptor and human glycine receptor (GlyR) α1β with IC50s >3 μM, and less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G with IC50s of 0.706 and 0.149 μM respectively.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    microtubule-associated protein 2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1207727-04-5
  • Formula Weight
    663.3
  • Molecular Formula
    C25H14BrF11N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN(C(=O)c1ccccc1)c1cccc(C(=O)Nc2c(Br)cc(cc2C(F)(F)F)C(F)(C(F)(F)F)C(F)(F)F)c1F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fontaine-Lenoir V, et, al. Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4711-6.
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