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CAY10444
CAS No. 298186-80-8
CAY10444( —— )
Catalog No. M33970 CAS No. 298186-80-8
CAY10444 is an S1P3 specific antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 37 | Get Quote |
|
| 10MG | 65 | Get Quote |
|
| 25MG | 135 | Get Quote |
|
| 50MG | 227 | Get Quote |
|
| 100MG | 372 | Get Quote |
|
| 200MG | 505 | Get Quote |
|
| 500MG | 795 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCAY10444
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NoteResearch use only, not for human use.
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Brief DescriptionCAY10444 is an S1P3 specific antagonist.
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DescriptionCAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors.
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In VitroBML-241 inhibits increases in intracellular Ca2+ concentration via P2 receptor or α1A-adrenoceptor stimulation and α1A-adrenoceptor-mediated contraction of rat mesenteric artery, while it does not affect S1P3-mediated decrease of Forskolin-induced cyclic AMP accumulation.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number298186-80-8
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Formula Weight287.46
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Molecular FormulaC15H29NO2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 41.67 mg/mL (144.96 mM; Ultrasonic (<80°C)
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SMILESCCCCCCCCCCCC1N[C@@H](CS1)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Salvatore Salomone, et al. Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Front Pharmacol. 2011 Feb 22;2:9. ?
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