Irigenin
CAS No. 548-76-5
Irigenin( —— )
Catalog No. M18785 CAS No. 548-76-5
Irigenin has antifungal activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameIrigenin
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NoteResearch use only, not for human use.
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Brief DescriptionIrigenin has antifungal activity.
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DescriptionIrigenin has antifungal activity.
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In VitroIrigenin specifically targets α9β1 and α4β1 integrin binding sites on Extra Domain A (EDA) comprising LEU46, PHE47, PRO48, GLU58, LEU59 and GLN60 in its C-C loop. Irigenin binds to the C-C loop of EDA, thereby blocking its interaction with integrins on the cell surface and thus abrogating subsequent Epithelial-Mesenchymal transition.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorNF-κB
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Research AreaCancer|Infection|Inflammation/Immunology
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Indication——
Chemical Information
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CAS Number548-76-5
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Formula Weight360.32
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Molecular FormulaC18H16O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (277.54 mM)
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SMILESCOc1cc(cc(c1OC)O)c1coc2cc(c(c(c2c1=O)O)OC)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kwang Seok Ahn, et al. Inhibitory effects of Irigenin from the rhizomes of Belamcanda chinensis on nitric oxide and prostaglandin E2 production in murine macrophage RAW 264.7 cells. 2006, 78(20): 2336-2342.
molnova catalog
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