Irigenin( —— )

Catalog No. M18785 CAS No. 548-76-5

Irigenin has antifungal activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Irigenin
Note

Research use only, not for human use.
Brief Description

Irigenin has antifungal activity.
Description

Irigenin has antifungal activity.
In Vitro

Irigenin specifically targets α9β1 and α4β1 integrin binding sites on Extra Domain A (EDA) comprising LEU46, PHE47, PRO48, GLU58, LEU59 and GLN60 in its C-C loop. Irigenin binds to the C-C loop of EDA, thereby blocking its interaction with integrins on the cell surface and thus abrogating subsequent Epithelial-Mesenchymal transition.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

NF-κB
Research Area

Cancer|Infection|Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

548-76-5
Formula Weight

360.32
Molecular Formula

C18H16O8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (277.54 mM)
SMILES

COc1cc(cc(c1OC)O)c1coc2cc(c(c(c2c1=O)O)OC)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kwang Seok Ahn, et al. Inhibitory effects of Irigenin from the rhizomes of Belamcanda chinensis on nitric oxide and prostaglandin E2 production in murine macrophage RAW 264.7 cells. 2006, 78(20): 2336-2342.

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