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Biotin-PEG4-N3
CAS No. 875770-34-6
Biotin-PEG4-N3 ( —— )
Catalog No. M21903 CAS No. 875770-34-6
Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 35 | In Stock |
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| 25MG | 65 | In Stock |
|
| 50MG | 88 | In Stock |
|
| 100MG | 132 | In Stock |
|
| 200MG | 196 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBiotin-PEG4-N3
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NoteResearch use only, not for human use.
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Brief DescriptionBiotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DescriptionBiotin-C2-PEG3-azide is a biotin with the azide tag, it can be conjugated to antiviral inhibitors, for example, RYL-634, which shows excellent broad-spectrum inhibition activity against various pathogenic viruses, including hepatitis C virus, dengue virus, Zika virus, chikungunya virus, enterovirus.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPEGs
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Research Area——
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Indication——
Chemical Information
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CAS Number875770-34-6
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Formula Weight444.55
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Molecular FormulaC18H32N6O5S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NCCOCCOCCOCCN=[N+]=[N-])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yang Y, et al. Discovery, Optimization, and Target Identification of Novel Potent Broad-Spectrum Antiviral Inhibitors.J Med Chem. 2019 Apr 25;62(8):4056-4073.
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