Biotin-PEG4-N3

CAS No. 875770-34-6

Biotin-PEG4-N3 ( —— )

Catalog No. M21903 CAS No. 875770-34-6

Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 In Stock
25MG 65 In Stock
50MG 88 In Stock
100MG 132 In Stock
200MG 196 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Biotin-PEG4-N3
  • Note
    Research use only, not for human use.
  • Brief Description
    Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
  • Description
    Biotin-C2-PEG3-azide is a biotin with the azide tag, it can be conjugated to antiviral inhibitors, for example, RYL-634, which shows excellent broad-spectrum inhibition activity against various pathogenic viruses, including hepatitis C virus, dengue virus, Zika virus, chikungunya virus, enterovirus.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PEGs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    875770-34-6
  • Formula Weight
    444.55
  • Molecular Formula
    C18H32N6O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NCCOCCOCCOCCN=[N+]=[N-])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yang Y, et al. Discovery, Optimization, and Target Identification of Novel Potent Broad-Spectrum Antiviral Inhibitors.J Med Chem. 2019 Apr 25;62(8):4056-4073.
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