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Home - Products - Cell Cycle/DNA Damage - PARP - BYK204165

BYK204165

CAS No. 1104546-89-5

BYK204165( RT-017290 )

Catalog No. M21123 CAS No. 1104546-89-5

BYK204165 is a potent PARP inhibitor?(PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BYK204165
  • Note
    Research use only, not for human use.
  • Brief Description
    BYK204165 is a potent PARP inhibitor?(PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay).
  • Description
    BYK204165 is a potent PARP inhibitor?(PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    RT-017290
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    PARP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1104546-89-5
  • Formula Weight
    252
  • Molecular Formula
    C15H12N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (495.50 mM; Need ultrasonic)
  • SMILES
    Cn1cccc1C=C1C(=O)NC(=O)c2ccccc21
  • Chemical Name
    (4Z)-4-[(1-methylpyrrol-2-yl)methylidene]isoquinoline-13-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Eltze T Boer R Wagner T et al. Imidazoquinolinone imidazopyridine and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.[J]. molecular pharmacology 2008 74(6):1587-1598.
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