Cart
sales@molnova.com
AG-14361
CAS No. 328543-09-5
AG-14361( AG14361 | AG-14361 | AG 14361. )
Catalog No. M14073 CAS No. 328543-09-5
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 121 | In Stock |
|
| 2MG | 67 | In Stock |
|
| 5MG | 110 | In Stock |
|
| 10MG | 202 | In Stock |
|
| 25MG | 394 | In Stock |
|
| 50MG | 564 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAG-14361
-
NoteResearch use only, not for human use.
-
Brief DescriptionAG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides.
-
DescriptionAG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides.
-
In Vitro——
-
In Vivo——
-
SynonymsAG14361 | AG-14361 | AG 14361.
-
PathwayCell Cycle/DNA Damage
-
TargetPARP
-
RecptorPARP1
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number328543-09-5
-
Formula Weight320.39
-
Molecular FormulaC19H20N4O
-
Purity>98% (HPLC)
-
SolubilityDMSO: 12 mg/mL (37.45 mM)
-
SMILESO=C1C2=C3C(N=C(C4=CC=C(CN(C)C)C=C4)N3CCN1)=CC=C2
-
Chemical Name1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one.
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Calabrese CR, et al. J Natl Y Inst, 2004, 96(1), 56-67.
molnova catalog
related products
-
AZ9482
AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.
-
Rucaparib Camsylate
Rucaparib Camsylate is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains. Rucaparib is the most effective PARP inhibitor in enzyme assays (Ki: 1.4 nM). Rucaparib inhibits PARP-1 activity by 97.1% at a concentration of 1 μM in permeabilized D283Med cells.
-
SRI-011381
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
