BRD9-IN-28 ( —— )

Catalog No. M13046 CAS No. 1947372-67-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

BRD9-IN-28
Note

Research use only, not for human use.
Brief Description

BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9.
Description

BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9; slightly less potent against BRD7 (Kd=368 nM) and completely inactive against BAZ2B, little affinity across BRD proteins from sub-families 1-3 and 5-8, including BAZ2A and BAZ2B; shows weak affinity for the BRDs from CBP, p300 and FALZ.
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Bromodomain
Recptor

Bromodomain
Research Area

——
Indication

——

CAS Number

1947372-67-9
Formula Weight

360.42
Molecular Formula

C21H20N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

1-(1-(imidazo[1,2-a]pyridin-5-yl)-7-morpholinoindolizin-3-yl)ethan-1-one

1. Duncan. A. Hay, et al. Med. Chem. Commun., 2015, DOI: 10.1039/C5MD00152H.

Calculator

molnova catalog