BRD2492

CAS No. 1821669-43-5

BRD2492 ( BRD 2492 )

Catalog No. M12810 CAS No. 1821669-43-5

BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BRD2492
  • Note
    Research use only, not for human use.
  • Brief Description
    BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively).
  • Description
    BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation.
  • Synonyms
    BRD 2492
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1821669-43-5
  • Formula Weight
    346.39
  • Molecular Formula
    C20H18N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC1=CC(C2=CC=NC=C2)=CC=C1N)C3=CC=C(NC(C)=O)C=C3
  • Chemical Name
    4-Acetylamino-N-(2-amino-5-pyridin-4-yl-phenyl)-benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wagner FF, et al. ACS Chem Biol. 2016 Feb 19;11(2):363-74.
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