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BRD2492

CAS No. 1821669-43-5

BRD2492 ( BRD 2492 )

Catalog No. M12810 CAS No. 1821669-43-5

BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively).

Purity : >98% (HPLC)

COA

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HNMR

HPLC

MSDS

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Biological Information

Product Name

BRD2492
Note

Research use only, not for human use.
Brief Description

BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively).
Description

BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation.
Synonyms

BRD 2492
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

HDAC
Research Area

——
Indication

——

Chemical Information

CAS Number

1821669-43-5
Formula Weight

346.39
Molecular Formula

C20H18N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=CC(C2=CC=NC=C2)=CC=C1N)C3=CC=C(NC(C)=O)C=C3
Chemical Name

4-Acetylamino-N-(2-amino-5-pyridin-4-yl-phenyl)-benzamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wagner FF, et al. ACS Chem Biol. 2016 Feb 19;11(2):363-74.

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