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BMS-901715
CAS No. 1699861-37-4
BMS-901715( BMS 901715 | BMS901715 )
Catalog No. M12595 CAS No. 1699861-37-4
BMS-901715 (BMS901715) is a?potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1503 | Get Quote |
|
| 50MG | 3042 | Get Quote |
|
| 100MG | 4140 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBMS-901715
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-901715 (BMS901715) is a?potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor.
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DescriptionBMS-901715 (BMS901715) is a?potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor.
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In VitroAdaptor associated kinase 1 (AAK1) is a member of the Ark1/Prk1 family of serine/threonine kinases. AAK1 mRNA exists in two splice forms termed short and long. The long form predominates and is highly expressed in brain and heart. AAK1 is enriched in synaptosomal preparations and is co-localized with endocytic structures in cultured cells. AAK1 modulates clatherin coated endocytosis, a process that is important in synaptic vesicle recycling and receptor-mediated endocytosis.
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In Vivo——
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SynonymsBMS 901715 | BMS901715
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PathwayOthers
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TargetAAK1
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RecptorAAK1
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Research Area——
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Indication——
Chemical Information
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CAS Number1699861-37-4
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Formula Weight448.535
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Molecular FormulaC22H28N10O
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)N1N=C(N=N1)C2=CC(=CC(=C2)O)NC3=NC=NN4C3=C(C=C4)CN5CCC(CC5)N
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Chemical Name3-((5-((4-aminopiperidin-1-yl)methyl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-5-(2-isopropyl-2H-tetrazol-5-yl)phenol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kostich W, et al. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.
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