BMS-901715

CAS No. 1699861-37-4

BMS-901715( BMS 901715 | BMS901715 )

Catalog No. M12595 CAS No. 1699861-37-4

BMS-901715 (BMS901715) is a?potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BMS-901715
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS-901715 (BMS901715) is a?potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor.
  • Description
    BMS-901715 (BMS901715) is a?potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor.
  • In Vitro
    Adaptor associated kinase 1 (AAK1) is a member of the Ark1/Prk1 family of serine/threonine kinases. AAK1 mRNA exists in two splice forms termed short and long. The long form predominates and is highly expressed in brain and heart. AAK1 is enriched in synaptosomal preparations and is co-localized with endocytic structures in cultured cells. AAK1 modulates clatherin coated endocytosis, a process that is important in synaptic vesicle recycling and receptor-mediated endocytosis.
  • In Vivo
    ——
  • Synonyms
    BMS 901715 | BMS901715
  • Pathway
    Others
  • Target
    AAK1
  • Recptor
    AAK1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1699861-37-4
  • Formula Weight
    448.535
  • Molecular Formula
    C22H28N10O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)N1N=C(N=N1)C2=CC(=CC(=C2)O)NC3=NC=NN4C3=C(C=C4)CN5CCC(CC5)N
  • Chemical Name
    3-((5-((4-aminopiperidin-1-yl)methyl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-5-(2-isopropyl-2H-tetrazol-5-yl)phenol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kostich W, et al. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.
molnova catalog
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