Cart
sales@molnova.com
BAZ2-ICR
CAS No. 1665195-94-7
BAZ2-ICR ( BAZ2 ICR )
Catalog No. M12539 CAS No. 1665195-94-7
BAZ2-ICR is a potent, selective and cell-active inhibitor of BAZ2A and BAZ2B bromodomains.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBAZ2-ICR
-
NoteResearch use only, not for human use.
-
Brief DescriptionBAZ2-ICR is a potent, selective and cell-active inhibitor of BAZ2A and BAZ2B bromodomains.
-
DescriptionBAZ2-ICR is a potent, selective and cell-active inhibitor of BAZ2A (Kd=109 nM; IC50=130 nM) and BAZ2B (Kd=170 nM; IC50=180 nM) bromodomains; demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains.
-
SynonymsBAZ2 ICR
-
PathwayChromatin/Epigenetic
-
TargetBromodomain
-
RecptorBromodomain
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1665195-94-7
-
Formula Weight357.42
-
Molecular FormulaC20H19N7
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2
-
Chemical Name4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Drouin L, et al. J Med Chem. 2015 Mar 12;58(5):2553-9.
molnova catalog
related products
-
ZL0454
ZL0454 is a potent, highly selective small-molecule BRD4 inhibitor with IC50 of 49 and 32 nM for BRD4-BD1 and BRD4-BD2, respectively.
-
BRD9-IN-28
BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9.
-
ZL0420
ZL0420 is a potent, highly selective BRD4 inhibitor with IC50 of 27 and 32 nM for BRD4-BD1 and BRD4-BD2, respectively.
