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Azoramide

CAS No. 932986-18-0

Azoramide ( Azoramide )

Catalog No. M19268 CAS No. 932986-18-0

Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 47 In Stock
25MG 91 In Stock
50MG 142 In Stock
100MG 259 In Stock
500MG 624 In Stock
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Biological Information

  • Product Name
    Azoramide
  • Note
    Research use only, not for human use.
  • Brief Description
    Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
  • Description
    Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. Azoramide mproves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress in multiple systems. Azoramide also exhibited potent antidiabetic efficacy in two independent mouse models of obesity by improving insulin sensitivity and pancreatic β cell function. Azoramide can be potential drug candidate for type 2 diabetes.
  • Synonyms
    Azoramide
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Endocrinology
  • Indication
    ——

Chemical Information

  • CAS Number
    932986-18-0
  • Formula Weight
    308.82
  • Molecular Formula
    C15H17ClN2OS
  • Purity
    98%
  • Solubility
    DMSO : ≥ 30 mg/mL; 97.14 mM
  • SMILES
    CCCC(=O)NCCc1csc(n1)-c1ccc(Cl)cc1
  • Chemical Name
    N-[2-[2-(4-chlorophenyl)-4-thiazolyl]ethyl]-butanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fu S, et al. Sci Transl Med. 2015 Jun 17;7(292):292ra98. doi: 10.1126/scitranslmed.aaa9134. Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.
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