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Pep 2-8
CAS No. 1541011-97-5
Pep 2-8( —— )
Catalog No. M21916 CAS No. 1541011-97-5
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 288 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePep 2-8
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NoteResearch use only, not for human use.
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Brief DescriptionProprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
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DescriptionProprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
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In VitroCell Viability Assay Cell Line:HepG2 cell.Concentration:15 μg/mL.Incubation Time:4 h.Result:Inhibited PCSK9 activity.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research Area——
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Indication——
Chemical Information
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CAS Number1541011-97-5
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Formula Weight1715.88
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Molecular FormulaC83H110N16O24
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (58.28 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang et al (2014) Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J.Biol.Chem.
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