Avoralstat ( BCX4161 )

Catalog No. M24967 CAS No. 918407-35-9

Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Avoralstat
Note

Research use only, not for human use.
Brief Description

Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
Description

Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
Synonyms

BCX4161
Pathway

Others
Target

Other Targets
Recptor

plasma kallikrein (PKK)
Research Area

——
Indication

——

Chemical Information

CAS Number

918407-35-9
Formula Weight

513.5
Molecular Formula

C28H27N5O5
Purity

>98% (HPLC)
Solubility

DMSO:50 mg/mL (97.36 mM; Need ultrasonic)
SMILES

COc(c(C=C)c1)cc(-c2ccc(C(NCC3CC3)=O)nc2C(O)=O)c1C(Nc(cc1)ccc1C(N)=N)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat. J Allergy Clin Immunol. 2016 Sep;138(3):934-936.e5.

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