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DOTMA

CAS No. 104872-42-6

DOTMA( —— )

Catalog No. M37606 CAS No. 104872-42-6

DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	54	In Stock
5MG	35	In Stock
10MG	50	In Stock
25MG	85	In Stock
50MG	133	In Stock
100MG	219	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

DOTMA
Note

Research use only, not for human use.
Brief Description

DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy.
Description

DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

104872-42-6
Formula Weight

670.58
Molecular Formula

C42H84ClNO2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 12.5 mg/mL (18.64 mM; Ultrasonic (<60°C)
SMILES

[Cl-].CCCCCCCC\C=C\CCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCC\C=C\CCCCCCCC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Aime S, et al. Properties, solution state behavior, and crystal structures of chelates of DOTMA. Inorg Chem. 2011;50(17):7955-7965.?

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