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Avatrombopag

CAS No. 570406-98-3

Avatrombopag ( AKR-501; E5501; YM477 )

Catalog No. M20798 CAS No. 570406-98-3

Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 76 In Stock
5MG 111 In Stock
10MG 177 In Stock
25MG 321 In Stock
50MG 537 In Stock
100MG 767 In Stock
500MG 1557 In Stock
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Biological Information

  • Product Name
    Avatrombopag
  • Note
    Research use only not for human use.
  • Brief Description
    Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
  • Description
    Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
  • Synonyms
    AKR-501; E5501; YM477
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TPO
  • Research Area
    Cardiovascular Disease
  • Indication
    Idiopathic thrombocytopenic purpura

Chemical Information

  • CAS Number
    570406-98-3
  • Formula Weight
    649.65
  • Molecular Formula
    C29H34Cl2N6O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:32 mg/mL (49.26 mM)
  • SMILES
    O=C(Nc1nc(-c2cc(Cl)cs2)c(N2CCN(C3CCCCC3)CC2)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xu H Cai R.Avatrombopag for the treatment of thrombocytopenia in patients with chronic liver disease.Expert Rev Clin Pharmacol. 2019 Sep;12(9):859-865?
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