Avanafil
CAS No. 330784-47-9
Avanafil ( TA1790;TA 1790;TA-1790 )
Catalog No. M14101 CAS No. 330784-47-9
A potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
25MG | 42 | In Stock |
|
50MG | 52 | In Stock |
|
100MG | 85 | In Stock |
|
200MG | 102 | In Stock |
|
500MG | 125 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAvanafil
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction.
-
DescriptionA potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction; shows no significant effect on PDE1, PDE6 and PDE11.Sexual Dysfunction Approved
-
SynonymsTA1790;TA 1790;TA-1790
-
PathwayAngiogenesis
-
TargetPDE
-
RecptorPDE5
-
Research AreaEndocrinology
-
IndicationSexual Dysfunction
Chemical Information
-
CAS Number330784-47-9
-
Formula Weight483.95
-
Molecular FormulaC23H26ClN7O3
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(C1=CN=C(N2[C@H](CO)CCC2)N=C1NCC3=CC=C(OC)C(Cl)=C3)NCC4=NC=CC=N4
-
Chemical Name5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kotera J, et al. J Urol. 2012 Aug;188(2):668-74.
2. Limin M, et al. Expert Opin Investig Drugs. 2010 Nov;19(11):1427-37.
3. Wang R, et al. J Sex Med. 2012 Aug;9(8):2122-9.
2. Limin M, et al. Expert Opin Investig Drugs. 2010 Nov;19(11):1427-37.
3. Wang R, et al. J Sex Med. 2012 Aug;9(8):2122-9.
molnova catalog
related products
-
NSP-805
NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.
-
Carbodenafil
Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).
-
Difamilast
Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).