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Difamilast
CAS No. 937782-05-3
Difamilast ( OPA-15406;OPA15406 )
Catalog No. M16718 CAS No. 937782-05-3
Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 295 | Get Quote |
|
| 10MG | 475 | Get Quote |
|
| 25MG | 773 | Get Quote |
|
| 50MG | 1071 | Get Quote |
|
| 100MG | 1422 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDifamilast
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NoteResearch use only, not for human use.
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Brief DescriptionDifamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).
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DescriptionDifamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).Dermatitis Phase 2 Clinical
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SynonymsOPA-15406;OPA15406
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE
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Research AreaInflammation/Immunology
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IndicationDermatitis
Chemical Information
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CAS Number937782-05-3
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Formula Weight446.45
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Molecular Formula3H24F2N2O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NCC1=COC(C2=CC=C(OC(F)F)C(OC(C)C)=C2)=N1)C3=CC=CC=C3OCC
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Chemical NameN-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)-2-ethoxybenzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hanifin JM, et al. J Am Acad Dermatol. 2016 Aug;75(2):297-305.
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