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Atazanavir

CAS No. 198904-31-3

Atazanavir( BMS-232632 )

Catalog No. M13109 CAS No. 198904-31-3

A highly potent HIV-1 protease inhibitor that exhibits potent anti-HIV activity EC50 of 2.6-5.3 nM and EC90 of 9-15 nM in cell culture.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Atazanavir
  • Note
    Research use only, not for human use.
  • Brief Description
    A highly potent HIV-1 protease inhibitor that exhibits potent anti-HIV activity EC50 of 2.6-5.3 nM and EC90 of 9-15 nM in cell culture.
  • Description
    A highly potent HIV-1 protease inhibitor that exhibits potent anti-HIV activity EC50 of 2.6-5.3 nM and EC90 of 9-15 nM in cell culture; shows synergistic antiviral effects in HIV-infected PBMCs; used to treat and prevent HIV/AIDS.HIV Infection Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BMS-232632
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIVProtease
  • Research Area
    Infection
  • Indication
    HIV Infection

Chemical Information

  • CAS Number
    198904-31-3
  • Formula Weight
    704.8555
  • Molecular Formula
    C38H52N6O7
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC
  • Chemical Name
    2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3S,8S,9S,12S)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Robinson BS, et al. Antimicrob Agents Chemother. 2000 Aug;44(8):2093-9. 2. Gong YF, et al. Antimicrob Agents Chemother. 2000 Sep;44(9):2319-26. 3. Drusano GL, et al. J Infect Dis. 2001 Apr 1;183(7):1126-9.
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