Ataciguat ( HMR-1766 )

Catalog No. M27435 CAS No. 254877-67-3

Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Ataciguat
Note

Research use only, not for human use.
Brief Description

Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
Description

Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.(In Vitro):Ataciguat induces the relaxation in aortic rings or coronary rings. In the presence of nitric oxide synthase (NOS) inhibitor, the endothelium effect was abolished to DETA-NO or ataciguat, in both vessels. Ataciguat was able to induce NO production in HUVECs cells. In the presence of NOS inhibitor, the NO production induced by ataciguat was abolished.
Synonyms

HMR-1766
Pathway

Others
Target

Other Targets
Recptor

PGE;ATPase;Potassium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

254877-67-3
Formula Weight

576.5
Molecular Formula

C21H19Cl2N3O6S3
Purity

>98% (HPLC)
Solubility

——
SMILES

Clc1ccc(s1)S(=O)(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kim DH, et al. Metabolism of liriodendrin and syringin by human intestinal bacteria and their relation to in vitro cytotoxicity. Arch Pharm Res. 1999 Feb;22(1):30-4.

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