Arimoclomol

CAS No. 289893-25-0

Arimoclomol( BRX-220 free base )

Catalog No. M26548 CAS No. 289893-25-0

Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 393 Get Quote
10MG 581 Get Quote
25MG 888 Get Quote
50MG 1242 Get Quote
100MG 1674 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Arimoclomol
  • Note
    Research use only, not for human use.
  • Brief Description
    Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).
  • Description
    Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).(In Vivo):In male Wistar rats, Arimoclomol (20 mg/kg; gavage) protects cholecystokinin-octapeptide (CCK)-induced acute pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased.
  • In Vitro
    ——
  • In Vivo
    Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect againstcholecystokinin-octapeptide (CCK)-induced acute pancreatitis. Animal Model:Male Wistar rats weighing 240 to 270 gDosage:20 mg/kg Administration:Administered intragastrically, for 5 daysResult:Had a protective effect against CCK-induced acute pancreatitis.
  • Synonyms
    BRX-220 free base
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    AP-1| LOX| NF-κB| Parasite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    289893-25-0
  • Formula Weight
    313.78
  • Molecular Formula
    C14H20ClN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@@H](CO\N=C(/Cl)c1cccn(=O)c1)CN1CCCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hadjipavlou-Litina D, et al. Kukoamine A analogs with lipoxygenase inhibitory activity. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1188-93.
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