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Amcasertib
CAS No. 1129403-56-0
Amcasertib ( BBI-503 )
Catalog No. M10454 CAS No. 1129403-56-0
A small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 106 | In Stock |
|
| 10MG | 176 | In Stock |
|
| 25MG | 372 | In Stock |
|
| 50MG | 556 | In Stock |
|
| 100MG | 791 | In Stock |
|
| 500MG | 1611 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAmcasertib
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NoteResearch use only, not for human use.
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Brief DescriptionA small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.
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DescriptionA small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases; targets and inhibits one or more pathways involved in cancer stem cell survival, shows potential antineoplastic activity.Liver Cancer Phase 2 Clinical
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SynonymsBBI-503
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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IndicationLiver Cancer
Chemical Information
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CAS Number1129403-56-0
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Formula Weight539.69
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Molecular FormulaC31H33N5O2S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESO=C(C1=C(C)NC(/C=C2C(NC3=C/2C=C(C4=CSC(C5=CC=CC=C5)=N4)C=C3)=O)=C1C)NCCN(CC)CC
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Chemical Name1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[[1,2-dihydro-2-oxo-5-(2-phenyl-4-thiazolyl)-3H-indol-3-ylidene]methyl]-2,4-dimethyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Marcucci F, et al. Front Oncol. 2016 May 10;6:115.
2. Iv Santaliz-Ruiz LE, et al. Int J Cancer. 2014 Dec 15;135(12):2741-8.
2. Iv Santaliz-Ruiz LE, et al. Int J Cancer. 2014 Dec 15;135(12):2741-8.
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