Allopregnanolone
CAS No. 516-54-1
Allopregnanolone( 3α,5α-THP | SAGE547 | SAGE 547 | SAGE-547 )
Catalog No. M14799 CAS No. 516-54-1
An endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
|
| 5MG | 87 | In Stock |
|
| 10MG | 142 | In Stock |
|
| 50MG | 553 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAllopregnanolone
-
NoteResearch use only, not for human use.
-
Brief DescriptionAn endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.
-
DescriptionAn endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.
-
In Vitro——
-
In Vivo——
-
Synonyms3α,5α-THP | SAGE547 | SAGE 547 | SAGE-547
-
PathwayMembrane Transporter/Ion Channel
-
TargetGAT
-
RecptorGABA
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number516-54-1
-
Formula Weight318.49346
-
Molecular FormulaC21H34O2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM
-
SMILESCC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
-
Chemical NamePregnan-20-one, 3-hydroxy-, (3α,5α)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Reddy DS, et al. Prog Brain Res. 2010;186:113-37.
2. Pinna G, et al. Neuropharmacology. 2000 Jan 28;39(3):440-8.
3. Kokate TG, et al. J Pharmacol Exp Ther. 1994 Sep;270(3):1223-9.
molnova catalog
related products
-
NNC 05-2090 hydrochl...
NNC 05-2090 is a potent selective GABA transporter inhibitor of mGAT2 with Ki of 1.4 uM.
-
LAU159
LAU159 is a potent, functionally selective positive modulator of α6β3γ2 GABAA receptor.
-
GR3027
GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC.
Cart
sales@molnova.com