AZD8542

CAS No. 1126366-36-6

AZD8542( —— )

Catalog No. M34171 CAS No. 1126366-36-6

AZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 506 Get Quote
5MG 751 Get Quote
10MG 1064 Get Quote
25MG 1536 Get Quote
50MG 2006 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    AZD8542
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].
  • Description
    AZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a? Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Hedgehog (Hh)
  • Recptor
    Hedgehog/Smoothened | Smo
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1126366-36-6
  • Formula Weight
    412.48
  • Molecular Formula
    C25H24N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC1=CC(C=2N=CN(C2)C)=C(C=C1C)C)C3=CC=C(OCC4=NC=CC=C4)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157.
molnova catalog
related products
  • LDE225

    LDE225 (NVP-LDE225; Erismodegib) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.

  • Tolnaftate

    Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.

  • Naftifine hydrochlor...

    Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity.