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AS-041164
CAS No. 6318-41-8
AS-041164 ( —— )
Catalog No. M24635 CAS No. 6318-41-8
AS-041164 is a selective and orally active PI3Kγ isoform inhibitor(IC50 of 70 nM), and shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 58 | In Stock |
|
| 25MG | 111 | In Stock |
|
| 50MG | 204 | In Stock |
|
| 100MG | 329 | In Stock |
|
| 200MG | 435 | In Stock |
|
| 500MG | 710 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAS-041164
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NoteResearch use only, not for human use.
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Brief DescriptionAS-041164 is a selective and orally active PI3Kγ isoform inhibitor(IC50 of 70 nM), and shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively).
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DescriptionAS-041164 is a selective and orally active PI3Kγ isoform inhibitor(IC50 of 70 nM), and shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). It has anti-inflammatory effects.
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3Kα;PI3Kβ;PI3Kγ;PI3Kδ
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Research Area——
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Indication——
Chemical Information
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CAS Number6318-41-8
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Formula Weight249.2
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Molecular FormulaC11H7NO4S
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (501.52 mM; Need ultrasonic)
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SMILESO=C(N1)/C(SC1=O)=C/C2=CC=C3C(OCO3)=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chiara Ferrandi, et al. Phosphoinositide 3-kinase gamma inhibition plays a crucial role in early steps of inflammation by blocking neutrophil recruitment. J Pharmacol Exp Ther. 2007 Sep;322(3):923-30.
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