ARN-2966

CAS No. 102212-26-0

ARN-2966( ARN2966 | ARN 2966 )

Catalog No. M10104 CAS No. 102212-26-0

ARN-2966 is a potent, BBB penetrant post-transcriptional modulator of APP expression in transfected CHO cells that produce amyloid precursor protein (APP).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 65 In Stock
10MG 110 In Stock
25MG 222 In Stock
50MG 357 In Stock
100MG 530 In Stock
500MG 1152 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ARN-2966
  • Note
    Research use only, not for human use.
  • Brief Description
    ARN-2966 is a potent, BBB penetrant post-transcriptional modulator of APP expression in transfected CHO cells that produce amyloid precursor protein (APP).
  • Description
    ARN-2966 is a potent, BBB penetrant post-transcriptional modulator of APP expression in transfected CHO cells that produce amyloid precursor protein (APP); reduces expression of APP with resultant lower production of Aβ; improves the memory and reduces Aβ in AD transgenic mice; orally active.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ARN2966 | ARN 2966
  • Pathway
    Others
  • Target
    Amyloids
  • Recptor
    Amyloids
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    102212-26-0
  • Formula Weight
    200.2365
  • Molecular Formula
    C12H12N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 43.4 mg/mL
  • SMILES
    C1=CC=C(C(=C1)NCC2=CC=CC=N2)O
  • Chemical Name
    Phenol, 2-[(2-pyridinylmethyl)amino]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ayodeji Asuni, et al. DOI: http://dx.doi.org/10.1016/j.jalz.2013.08.025
molnova catalog
related products
  • TDI-2760

    TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction.

  • Aβ polymerization st...

    Aβ polymerization stimulator O4 is an orcein-related small molecule can drive polymerization of amyloid-β (Aβ).

  • FPS-ZM1

    FPS-ZM1 is a high-affinity RAGE-specific inhibitor.