TDI-2760

CAS No. 956128-08-8

TDI-2760( TDI2760 )

Catalog No. M16824 CAS No. 956128-08-8

TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    TDI-2760
  • Note
    Research use only, not for human use.
  • Brief Description
    TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction.
  • Description
    TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process; restores the Aβ42-induced decrease in fibrin clot turbidity without affecting normal clotting in an in vitro clotting assay, effectively inhibits Aβ42 fibrillization and modulates Aβ42-induced contact system activation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    TDI2760
  • Pathway
    Others
  • Target
    Amyloids
  • Recptor
    Amyloids
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    956128-08-8
  • Formula Weight
    306.369
  • Molecular Formula
    C18H18N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    5-(3-(dimethylamino)phenoxy)-N-phenylpyrimidin-2-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Singh PK, et al. Biochemistry. 2018 Feb 27;57(8):1399-1409.
molnova catalog
related products
  • Aβ polymerization st...

    Aβ polymerization stimulator O4 is an orcein-related small molecule can drive polymerization of amyloid-β (Aβ).

  • GSK-3039294

    GSK-3039294 is an orally available small molecule inhibitor of serum amyloid P component (SAP).

  • FPS-ZM1

    FPS-ZM1 is a high-affinity RAGE-specific inhibitor.