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Home - Products - GPCR/G Protein - Cannabinoid Receptor - AM1241

AM1241

CAS No. 444912-48-5

AM1241( AM-1241 | AM 1241 )

Catalog No. M14524 CAS No. 444912-48-5

A potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 29 Get Quote
5MG 42 Get Quote
10MG 73 Get Quote
25MG 162 Get Quote
50MG 275 Get Quote
100MG 496 Get Quote
500MG 1071 Get Quote
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Biological Information

  • Product Name
    AM1241
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM.
  • Description
    A potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM, >80-fold selectivity over CB1 receptors in radioligand binding assay; suppresses spinal fos protein expression and pain behavior in a rat model of inflammation, dose-dependently reversed tactile and thermal hypersensitivity produced by ligation of the L5 and L6 spinal nerves in rats.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AM-1241 | AM 1241
  • Pathway
    GPCR/G Protein
  • Target
    Cannabinoid Receptor
  • Recptor
    CB1| CB2
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    444912-48-5
  • Formula Weight
    503.3
  • Molecular Formula
    C22H22IN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN1CCCCC1Cn2cc(c3c2cccc3)C(=O)c4cc(ccc4I)[N+](=O)[O-]
  • Chemical Name
    (2-iodo-5-nitrophenyl)-(1-(1-methylpiperidin-2-ylmethyl)-1H-indol-3-yl)methanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Malan TP Jr, et al. Pain. 2001 Sep;93(3):239-45. 2. Nackley AG, et al. Neuroscience. 2003;119(3):747-57. 3. Yao BB, et al. Br J Pharmacol. 2006 Sep;149(2):145-54. 4. Ibrahim MM, et al. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10529-33.
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