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AM1241
CAS No. 444912-48-5
AM1241( AM-1241 | AM 1241 )
Catalog No. M14524 CAS No. 444912-48-5
A potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | Get Quote |
|
| 5MG | 42 | Get Quote |
|
| 10MG | 73 | Get Quote |
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| 25MG | 162 | Get Quote |
|
| 50MG | 275 | Get Quote |
|
| 100MG | 496 | Get Quote |
|
| 500MG | 1071 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAM1241
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM.
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DescriptionA potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM, >80-fold selectivity over CB1 receptors in radioligand binding assay; suppresses spinal fos protein expression and pain behavior in a rat model of inflammation, dose-dependently reversed tactile and thermal hypersensitivity produced by ligation of the L5 and L6 spinal nerves in rats.
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In Vitro——
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In Vivo——
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SynonymsAM-1241 | AM 1241
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCB1| CB2
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number444912-48-5
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Formula Weight503.3
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Molecular FormulaC22H22IN3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1CCCCC1Cn2cc(c3c2cccc3)C(=O)c4cc(ccc4I)[N+](=O)[O-]
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Chemical Name(2-iodo-5-nitrophenyl)-(1-(1-methylpiperidin-2-ylmethyl)-1H-indol-3-yl)methanone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Malan TP Jr, et al. Pain. 2001 Sep;93(3):239-45.
2. Nackley AG, et al. Neuroscience. 2003;119(3):747-57.
3. Yao BB, et al. Br J Pharmacol. 2006 Sep;149(2):145-54.
4. Ibrahim MM, et al. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10529-33.
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