AG-1517

CAS No. 153436-54-5

AG-1517 ( PD153035 )

Catalog No. M12162 CAS No. 153436-54-5

PD153035 hydrochloride is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 52 In Stock
25MG 109 In Stock
50MG 203 In Stock
100MG 354 In Stock
200MG 530 In Stock
500MG 831 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AG-1517
  • Note
    Research use only, not for human use.
  • Brief Description
    PD153035 hydrochloride is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src.
  • Description
    PD153035 hydrochloride is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src.
  • Synonyms
    PD153035
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    153436-54-5
  • Formula Weight
    360.21
  • Molecular Formula
    C16H14BrN3O2
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    COC1=C(OC)C=C2C(NC3=CC(Br)=CC=C3)=NC=NC2=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fry DW, et al. Science. 1994, 265(5175), 1093-1095.
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