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Daphnetin
CAS No. 486-35-1
Daphnetin ( 7,8-Dihydroxycoumarin; NSC 633563 )
Catalog No. M14627 CAS No. 486-35-1
Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 39 | In Stock |
|
| 25MG | 78 | In Stock |
|
| 50MG | 152 | In Stock |
|
| 100MG | 230 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDaphnetin
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NoteResearch use only, not for human use.
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Brief DescriptionDaphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.
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DescriptionDaphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.
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Synonyms7,8-Dihydroxycoumarin; NSC 633563
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR; PKA; PKC
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number486-35-1
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Formula Weight178.14
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Molecular FormulaC9H6O4
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Purity>98%(HPLC)
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SolubilityDMSO: 35 mg/mL (196.47 mM)
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SMILESO=C1C=CC2=CC=C(O)C(O)=C2O1
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Chemical Name7,8-dihydroxy-2H-1-benzopyran-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yang EB, et al. Biochem Biophys Res Commun, 1999, 260(3), 682-685.
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