A-17
CAS No. 505057-98-7
A-17( Hsp90α inhibitor A17 )
Catalog No. M14721 CAS No. 505057-98-7
A potent Hsp90α/p23 interaction inhibitor with IC50 of 0.15 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameA-17
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent Hsp90α/p23 interaction inhibitor with IC50 of 0.15 uM.
-
DescriptionA potent Hsp90α/p23 interaction inhibitor with IC50 of 0.15 uM, more effective than CP-9 in degrading pAkt/total Akt and Raf-1; inhibits Hsp90(α/β)/p23 interactions and degrading Hsp90 client proteins in cell culture, but not in live mice.
-
In Vitro——
-
In Vivo——
-
SynonymsHsp90α inhibitor A17
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorHSP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number505057-98-7
-
Formula Weight384.333
-
Molecular FormulaC15H11F3N4O3S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name2-((4-(furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chan CT, et al. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2476-85.
molnova catalog
related products
-
Hexamethylene amilor...
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 μM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-2.4 μM for various NHE isoforms.
-
3-Phenyltoxoflavin
3-Phenyltoxoflavin is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.
-
Ochromycinone
STA-21 is a selective STAT3 inhibitor.
Cart
sales@molnova.com