4-Aminopyridine
CAS No. 504-24-5
4-Aminopyridine ( 4-AP; BRL 34915; Dalfampridine; Fampridine; NSC 15041 )
Catalog No. M14717 CAS No. 504-24-5
4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
50MG | 45 | In Stock |
|
100MG | Get Quote | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product Name4-Aminopyridine
-
NoteResearch use only, not for human use.
-
Brief Description4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
-
Description4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane. Target: Potassium Channel 4-Aminopyridine(4AP) is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
-
Synonyms4-AP; BRL 34915; Dalfampridine; Fampridine; NSC 15041
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorPotassium Channel
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number504-24-5
-
Formula Weight94.11
-
Molecular FormulaC5H6N2
-
Purity>98%(HPLC)
-
SolubilitySoluble in Water
-
SMILESC1=CN=CC=C1N
-
Chemical Namepyridin-4-amine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sherratt, R.M., H. Bostock, and T.A. Sears, Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres. nature, 1980. 283(5747): p. 570-2.
2. Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.
5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76.
2. Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.
5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76.
molnova catalog
related products
-
Gut restricted-7
Gut restricted-7 (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. It decreases gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice.
-
NS6180
NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation.
-
Mitiglinide calcium ...
An insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells.