4-Aminopyridine

CAS No. 504-24-5

4-Aminopyridine ( 4-AP; BRL 34915; Dalfampridine; Fampridine; NSC 15041 )

Catalog No. M14717 CAS No. 504-24-5

4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    4-Aminopyridine
  • Note
    Research use only, not for human use.
  • Brief Description
    4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
  • Description
    4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane. Target: Potassium Channel 4-Aminopyridine(4AP) is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
  • Synonyms
    4-AP; BRL 34915; Dalfampridine; Fampridine; NSC 15041
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    Potassium Channel
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    504-24-5
  • Formula Weight
    94.11
  • Molecular Formula
    C5H6N2
  • Purity
    >98%(HPLC)
  • Solubility
    Soluble in Water
  • SMILES
    C1=CN=CC=C1N
  • Chemical Name
    pyridin-4-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sherratt, R.M., H. Bostock, and T.A. Sears, Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres. nature, 1980. 283(5747): p. 570-2.
2. Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.
5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76.
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