P-1075
CAS No. 60559-98-0
P-1075 ( —— )
Catalog No. M26779 CAS No. 60559-98-0
P-1075 is a potent sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) activator (EC50 = 45 nM).
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
2MG | 72 | Get Quote |
|
5MG | 115 | Get Quote |
|
10MG | 192 | Get Quote |
|
25MG | 354 | Get Quote |
|
50MG | 530 | Get Quote |
|
100MG | 759 | Get Quote |
|
500MG | 1557 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameP-1075
-
NoteResearch use only, not for human use.
-
Brief DescriptionP-1075 is a potent sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) activator (EC50 = 45 nM).
-
DescriptionP-1075 is a potent sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) activator (EC50 = 45 nM). P-1075 opens opens mitoKATP channels and may be cardioprotective.
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorHuman Endogenous Metabolite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number60559-98-0
-
Formula Weight231.3
-
Molecular FormulaC12H17N5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCC(C)(C)N\C(NC#N)=N\c1cccnc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
VU591 hydrochloride
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM).?Thought to block the intracellular pore of the Kir1.1 channel.?Exhibits no effect on Kir7.1 at concentrations up to 10 μM;?does not inhibit Kir2.1, Kir2.3 or Kir4.1.?
-
Rimtuzalcap
Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels).
-
QO-40
QO-40 is a KCNQ2/3 potassium channels activator.QO-40 potently augmented KCNQ2/3 channels expressed in Chinese hamster ovary cells and shifted the half-maximal activation voltage (V(1/2)) in the hyperpolarizing direction.?The V(1/2) was negatively shifted in a concentration-dependent manner.?