2-Deoxy-2-fluoro-beta-D-arabinoguanosine( —— )

Catalog No. M37884 CAS No. 103884-98-6

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Datasheet

HNMR

HPLC

MSDS

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Product Name

2-Deoxy-2-fluoro-beta-D-arabinoguanosine
Note

Research use only, not for human use.
Brief Description

2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.
Description

2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
In Vitro

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In Vivo

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Synonyms

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Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis
Research Area

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Indication

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1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?

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