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NSC 146109 hydrochloride
CAS No. 59474-01-0
NSC 146109 hydrochloride( —— )
Catalog No. M26341 CAS No. 59474-01-0
NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 36 | In Stock |
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| 5MG | 32 | In Stock |
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| 10MG | 51 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNSC 146109 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionNSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
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DescriptionNSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.(In Vitro):NSC 146109 hydrochloride promotes breast cancer cells to undergo apoptosis through activating p53 and inducing the expression of proapoptotic genes.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorALK| ROS1
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Research Area——
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Indication——
Chemical Information
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CAS Number59474-01-0
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Formula Weight316.85
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Molecular FormulaC17H17ClN2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (263.00 mM)
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SMILESCl.Cc1c2ccccc2c(CSC(N)=N)c2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Guo M, et al. Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives. Eur J Med Chem. 2018 Sep 6;158:322-333.
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