NSC 146109 hydrochloride( —— )

Catalog No. M26341 CAS No. 59474-01-0

NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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2MG	31	Get Quote
5MG	52	Get Quote
10MG	82	Get Quote
25MG	131	Get Quote
50MG	196	Get Quote
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Biological Information

Product Name

NSC 146109 hydrochloride
Note

Research use only, not for human use.
Brief Description

NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
Description

NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.(In Vitro):NSC 146109 hydrochloride promotes breast cancer cells to undergo apoptosis through activating p53 and inducing the expression of proapoptotic genes.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

ALK| ROS1
Research Area

——
Indication

——

Chemical Information

CAS Number

59474-01-0
Formula Weight

316.85
Molecular Formula

C17H17ClN2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 83.33 mg/mL (263.00 mM)
SMILES

Cl.Cc1c2ccccc2c(CSC(N)=N)c2ccccc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Guo M, et al. Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives. Eur J Med Chem. 2018 Sep 6;158:322-333.

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