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116-9e

CAS No. 831217-43-7

116-9e( —— )

Catalog No. M34102 CAS No. 831217-43-7

116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibiting simian virus 40 (SV40) replication, tumour antigen (TAg) endogenous ATPase activity, and TAg-mediated activation of Hsp70. 116-9e can be used to study cancer drug resistance.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 73 Get Quote
5MG 107 Get Quote
10MG 179 Get Quote
25MG 363 Get Quote
50MG 609 Get Quote
100MG 861 Get Quote
200MG 1152 Get Quote
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Biological Information

  • Product Name
    116-9e
  • Note
    Research use only, not for human use.
  • Brief Description
    116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibiting simian virus 40 (SV40) replication, tumour antigen (TAg) endogenous ATPase activity, and TAg-mediated activation of Hsp70. 116-9e can be used to study cancer drug resistance.
  • Description
    116-9e (MAL2-11B) is a Hsp70 co-chaperone DNAJA1 inhibitor. 116-9e inhibits Simian Virus 40 (SV40) replication and DNA synthesis. 116-9e inhibits tumor antigen (TAg)’s endogenous ATPase activity and the TAg-mediated activation of Hsp70.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Virus Protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    831217-43-7
  • Formula Weight
    512.6
  • Molecular Formula
    C31H32N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (195.08 mM; Ultrasonic )
  • SMILES
    C(OCC1=CC=CC=C1)(=O)C=2C(NC(=O)N(CCCCCC(O)=O)C2C)C3=CC=C(C=C3)C4=CC=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Christine M Wright, et al.Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen. Virus Res. 2009 Apr;141(1):71-80.?
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