1-Ethynylpyrene ( —— )

Catalog No. M28844 CAS No. 34993-56-1

1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

1-Ethynylpyrene
Note

Research use only, not for human use.
Brief Description

1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).
Description

1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).(In Vitro):The Ki values of 1-Ethynylpyrene against P450 1A2, and 2B1 is 0.32 and 0.04 μM, respectively.
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

P450
Recptor

LFA-1;ICAM-1;IL-2
Research Area

——
Indication

——

Chemical Information

CAS Number

34993-56-1
Formula Weight

226.3
Molecular Formula

C18H10
Purity

>98% (HPLC)
Solubility

——
SMILES

C#Cc1ccc2ccc3cccc4ccc1c2c34
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Tazawa K, Koutsogiannaki S, Chamberlain M, Yuki K. The effect of different anesthetics on tumor cytotoxicity by natural killer cells. Toxicol Lett. 2017 Jan 15;266:23-31.

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