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Home - Products - Metabolic Enzyme/Protease - P450 - Mefentrifluconazole

Mefentrifluconazole

CAS No. 1417782-03-6

Mefentrifluconazole ( —— )

Catalog No. M23572 CAS No. 1417782-03-6

Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Mefentrifluconazole
  • Note
    Research use only, not for human use.
  • Brief Description
    Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor.
  • Description
    Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM).?Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent.?
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    CYP51A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1417782-03-6
  • Formula Weight
    397.8
  • Molecular Formula
    C18H15ClF3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL (251.40 mM; Need ultrasonic)
  • SMILES
    OC(C)(C1=CC=C(OC2=CC=C(Cl)C=C2)C=C1C(F)(F)F)CN3N=CN=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tesh SA, et al. Innovative selection approach for a new antifungal agent mefentrifluconazole (Revysol?) and the impact upon its toxicity profile. Regul Toxicol Pharmacol.?2019?Aug;106:152-168.
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