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(-)-Butin

CAS No. 492-14-8

(-)-Butin( —— )

Catalog No. M24449 CAS No. 492-14-8

(-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (-)-Butin
  • Note
    Research use only, not for human use.
  • Brief Description
    (-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction.
  • Description
    (-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SOD induction via the PI3K/Akt signaling pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    Akt|Nrf2|PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    492-14-8
  • Formula Weight
    272.25
  • Molecular Formula
    C15H12O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 190 mg/mL (697.89 mM)
  • SMILES
    O=C1C[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC=C13
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway.J Cell Biochem. 2012 Jun;113(6):1987-97.
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