λ-Cyhalothrin

CAS No. 91465-08-6

λ-Cyhalothrin ( Icon; Karate; lambda-Cyhalothrin )

Catalog No. M27894 CAS No. 91465-08-6

lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    λ-Cyhalothrin
  • Note
    Research use only, not for human use.
  • Brief Description
    lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.
  • Description
    lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.(In Vitro):The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes.λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro.λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control.λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles.(In Vivo):The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is significantly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min.
  • Synonyms
    Icon; Karate; lambda-Cyhalothrin
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Angiotensin-converting Enzyme (ACE)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    91465-08-6
  • Formula Weight
    449.9
  • Molecular Formula
    C23H19ClF3NO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1(C)[C@H](\C=C(/Cl)C(F)(F)F)[C@@H]1C(=O)O[C@@H](C#N)c1cccc(Oc2ccccc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ishizuka H, et al. Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR). J Pharmacol Exp Ther. 1997 Mar;280(3):1304-11.
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