λ-Cyhalothrin
CAS No. 91465-08-6
λ-Cyhalothrin( Icon | Karate | lambda-Cyhalothrin )
Catalog No. M27894 CAS No. 91465-08-6
lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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100MG | 37 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product Nameλ-Cyhalothrin
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NoteResearch use only, not for human use.
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Brief Descriptionlambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.
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Descriptionlambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.(In Vitro):The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes.λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro.λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control.λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles.(In Vivo):The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is significantly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min.
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In Vitro——
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In Vivo——
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SynonymsIcon | Karate | lambda-Cyhalothrin
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorAngiotensin-converting Enzyme (ACE)
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Research Area——
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Indication——
Chemical Information
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CAS Number91465-08-6
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Formula Weight449.85
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Molecular FormulaC23H19ClF3NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (74.09 mM)
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SMILESCC1(C)[C@H](\C=C(/Cl)C(F)(F)F)[C@@H]1C(=O)O[C@@H](C#N)c1cccc(Oc2ccccc2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ishizuka H, et al. Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR). J Pharmacol Exp Ther. 1997 Mar;280(3):1304-11.
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