
α-Humulene
CAS No. 6753-98-6
α-Humulene( Humulene | α-Caryophyllene )
Catalog No. M29088 CAS No. 6753-98-6
α-Humulene is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
100MG | 67 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product Nameα-Humulene
-
NoteResearch use only, not for human use.
-
Brief Descriptionα-Humulene is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression.
-
Descriptionα-Humulene is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression.(In Vitro):The cytotoxic activity was evaluated in cellular lines of breast cancer MCF-7, colon cancer HCT-116, and murine macrophage RAW264.7 cell lines by the MTT assay Results: the sub-subfraction F1.1.1 of S. officinalis essential oil containing alpha-humulene present highest activity on RAW264.7 and HCT-116 with IC(50) values of 41.9 and 77.3 mu g/ml, respectively. The sub-subfraction F1.2.1 of S. officinalis essential oil with trans-caryophyllene(Alpha-caryophyllene) showed less activity on RAW246.7 and HCT-116 with IC(50) values of 90.5 and 145.8 mu g/ml. The cytotoxicity of α-Humulene against human lung carcinoma A549, colon adenocarcinoma DLD-1, skin fibroblasts WS1 cell lines is 28±1, 43±3, and 24±3 μg/mL, respetctively.
-
In VitroThe cytotoxicity of α-Humulene against human lung carcinoma A549, colon adenocarcinoma DLD-1, skin fibroblasts WS1 cell lines is 28±1, 43±3, and 24±3 μg/mL, respetctively.
-
In Vivo——
-
SynonymsHumulene | α-Caryophyllene
-
PathwayApoptosis
-
TargetTNF
-
RecptorTNF
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number6753-98-6
-
Formula Weight204.357
-
Molecular FormulaC15H24
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 33.33 mg/mL (163.10 mM)
-
SMILESC\C1=C/CC(C)(C)\C=C\C\C(C)=C\CC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog



related products
-
CDC801
CDC801 is a potent and orally active inhibitor of PDE4 and TNF-α (IC50: 1.1 μM and 2.5 μM).
-
UCB-5307
UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro.
-
Pomalidomide
A potent inhibitor of TNF-α production; inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs.