bruceine B( —— )

Catalog No. M20422 CAS No. 25514-29-8

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Product Name

bruceine B
Note

Research use only, not for human use.
Brief Description

Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.
Description

Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.
In Vitro

Bruceine B exhibits an IC50 of 10 nM for antimalarial activity.
In Vivo

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Synonyms

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Pathway

Apoptosis
Target

TNF
Recptor

TNF-α
Research Area

——
Indication

——

CAS Number

25514-29-8
Formula Weight

480.5
Molecular Formula

C23H28O11
Purity

>98% (HPLC)
Solubility

——
SMILES

[H][C@]12[C@@H](OC(C)=O)C(=O)O[C@]3([H])C[C@@]4([H])C(C)=C(O)C(=O)C[C@]4(C)[C@@]4([H])[C@@H](O)[C@H](O)[C@]1(OC[C@@]234)C(=O)OC
Chemical Name

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1.Utoguchi N Nakata T Cheng H H et al. Bruceine B A Potent Inhibitor of Leukocyte-Endothelial Cell Adhesion[J]. Inflammation 1997 21(2):223-233.

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