α-Glucosidase-IN-23

CAS No. 161187-57-1

α-Glucosidase-IN-23( —— )

Catalog No. M35940 CAS No. 161187-57-1

α-Glucosidase-IN-23 is an orally active inhibitor of α-glucosidase that can decrease blood glucose levels by inhibiting α-glucosidase (IC50 = 4.48 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 299 Get Quote
5MG 454 Get Quote
10MG 621 Get Quote
25MG 911 Get Quote
50MG 1224 Get Quote
100MG 1575 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    α-Glucosidase-IN-23
  • Note
    Research use only, not for human use.
  • Brief Description
    α-Glucosidase-IN-23 is an orally active inhibitor of α-glucosidase that can decrease blood glucose levels by inhibiting α-glucosidase (IC50 = 4.48 μM).
  • Description
    α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 decreases blood glucose by a-glucosidase inhibition with an IC50 value of 4.48 μM. α-Glucosidase-IN-23 can be used for the research of diabetes.
  • In Vitro
    Cell Proliferation AssayCell Line:INS-1 Cells Concentration:1 μM Incubation Time:Result:Stimulated the growth of INS-1 cells in a dose-codependent approach.Apoptosis AnalysisCell Line:INS-1 Cells Concentration:1 μM Incubation Time:Result:Restored the viability of INS-1 cells by about five times from apoptosis and eight times from necrosis.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Glucosidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    161187-57-1
  • Formula Weight
    373.4
  • Molecular Formula
    C20H23NO6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(OCC)(=O)C=1C(C(C(OCC)=O)=C(C)NC1C)C2=C3C(=CC=C2)OCO3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Peter A Sidhom, et al. Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species. J Med Chem. 2023 Jan 12;66(1):991-1010. ?
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