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BT18

CAS No. 924811-53-0

BT18( —— )

Catalog No. M24975 CAS No. 924811-53-0

BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 72 In Stock
10MG 132 In Stock
25MG 242 In Stock
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Biological Information

  • Product Name
    BT18
  • Note
    Research use only, not for human use.
  • Brief Description
    BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF).
  • Description
    BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 has an effect on RET receptor tyrosine kinase RetA and GDNF family receptor GFRα1 function.
  • In Vitro
    BT18 (50 μM; 1-90 minutes) activates AKT and ERK1/2 in time-dependently in MG87RET cell lines.BT18 (1-50 μM; 90 minutes) activates AKT in a dose-dependent manner in MG87RET cell lines.BT18 (5-50 μM; 15 mimutes) appears to phosphorylate RET in concentration of 50 μM both in GFP-transfected and in GFRD1-transfected cells. Western Blot Analysis Cell Line:MG87RET cell lines Concentration:50 μM Incubation Time:1, 5, 15, 45, 90 minutes Result:Activated AKT and ERK1/2 in time-dependently.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    924811-53-0
  • Formula Weight
    637.64
  • Molecular Formula
    C30H31F4N3O6S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 98 mg/mL (153.69 mM; Need ultrasonic)
  • SMILES
    COc(ccc(S(N(CC1)Cc(cc2OC)c1cc2OC)(=O)=O)c1)c1N(CC1)CCN1C(c(cc1)c(C(F)(F)F)cc1F)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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