JNJ-38893777 ( JNJ38893777 )

Catalog No. M16802 CAS No. 951135-00-5

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Datasheet

HNMR

HPLC

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Product Name

JNJ-38893777
Note

Research use only, not for human use.
Brief Description

JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.
Description

JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.Pain Phase 1 Clinical
Synonyms

JNJ38893777
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

TRP/TRPV Channel
Research Area

Neurological Disease
Indication

Pain

CAS Number

951135-00-5
Formula Weight

536.53
Molecular Formula

C26H26F6N6
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

2-(1-piperidinyl)-N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine

1. Manitpisitkul P, et al. Clin Drug Investig. 2015 Jun;35(6):353-63.
2. Meents JE, et al. J Headache Pain. 2015;16:57.

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