m-PEG11-Br
CAS No. 1258596-39-2
m-PEG11-Br ( —— )
Catalog No. M23430 CAS No. 1258596-39-2
m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 45 | In Stock |
|
100MG | 91 | In Stock |
|
200MG | 137 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product Namem-PEG11-Br
-
NoteResearch use only, not for human use.
-
Brief Descriptionm-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
Descriptionm-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorPEGs
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1258596-39-2
-
Formula Weight579.5
-
Molecular FormulaC23H47BrO11
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCBr
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
MS4078
MS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM).
-
Amino-PEG11-amine
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.
-
Alkynyl Stearic Acid
Alkynyl Stearic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.