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Propargyl-PEG3-amine
CAS No. 932741-19-0
Propargyl-PEG3-amine( —— )
Catalog No. M33554 CAS No. 932741-19-0
Propargyl-PEG3-amine (Propargyl-PEG3-NH2) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 28 | In Stock |
|
| 200MG | 32 | In Stock |
|
| 500MG | 49 | In Stock |
|
| 1G | 75 | In Stock |
|
Biological Information
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Product NamePropargyl-PEG3-amine
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NoteResearch use only, not for human use.
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Brief DescriptionPropargyl-PEG3-amine (Propargyl-PEG3-NH2) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
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DescriptionPropargyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Propargyl-PEG3-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number932741-19-0
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Formula Weight187.24
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Molecular FormulaC9H17NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESC#CCOCCOCCOCCN
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
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