hDHODH-IN-5

CAS No. 2029049-77-0

hDHODH-IN-5 ( DHODH-IN-7 )

Catalog No. M26160 CAS No. 2029049-77-0

hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 152 Get Quote
10MG 221 Get Quote
25MG 356 Get Quote
50MG 530 Get Quote
100MG 755 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    hDHODH-IN-5
  • Note
    Research use only, not for human use.
  • Brief Description
    hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.
  • Description
    hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).(In Vitro):hDHODH-IN-5 induces differentiation in ER-HOX-GFP, THP1, and U937 human AML cell lines with EC50s of 3.6, 2.7, and 2.5 μM, respectively.
  • Synonyms
    DHODH-IN-7
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    p300
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2029049-77-0
  • Formula Weight
    390.4
  • Molecular Formula
    C21H21F3N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC(F)(F)c1ccc(cc1)C(=O)NCCC(=O)N[C@@H]1CCCc2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mantelingu K, et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. J Phys Chem B. 2007;111(17):4527-4534.
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