Cart
sales@molnova.com
hDHODH-IN-5
CAS No. 2029049-77-0
hDHODH-IN-5( DHODH-IN-7 )
Catalog No. M26160 CAS No. 2029049-77-0
hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 152 | Get Quote |
|
| 10MG | 221 | Get Quote |
|
| 25MG | 356 | Get Quote |
|
| 50MG | 530 | Get Quote |
|
| 100MG | 755 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamehDHODH-IN-5
-
NoteResearch use only, not for human use.
-
Brief DescriptionhDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.
-
DescriptionhDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).(In Vitro):hDHODH-IN-5 induces differentiation in ER-HOX-GFP, THP1, and U937 human AML cell lines with EC50s of 3.6, 2.7, and 2.5 μM, respectively.
-
SynonymsDHODH-IN-7
-
PathwayMetabolic Enzyme/Protease
-
TargetDehydrogenase
-
Recptorp300
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2029049-77-0
-
Formula Weight390.4
-
Molecular FormulaC21H21F3N2O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESFC(F)(F)c1ccc(cc1)C(=O)NCCC(=O)N[C@@H]1CCCc2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Mantelingu K, et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. J Phys Chem B. 2007;111(17):4527-4534.
molnova catalog
related products
-
AVN944
AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
-
Enoxolone
Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption.
-
IDH1-IN-1
Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 uM(A level in Patent).
