AGI-6780

CAS No. 1432660-47-3

AGI-6780 ( AGI6780; AGI 6780; AGI-6780 )

Catalog No. M11841 CAS No. 1432660-47-3

AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 40 In Stock
5MG 65 In Stock
10MG 110 In Stock
25MG 209 In Stock
50MG 372 In Stock
100MG 556 In Stock
500MG 1197 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AGI-6780
  • Note
    Research use only, not for human use.
  • Brief Description
    AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.
  • Description
    AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.
  • Synonyms
    AGI6780; AGI 6780; AGI-6780
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    IDH2 R140Q mutant
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1432660-47-3
  • Formula Weight
    481.51
  • Molecular Formula
    C21H18F3N3O3S2
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 96 mg/mL (199.37 mM); DMSO: 96 mg/mL (199.37 mM)
  • SMILES
    O=S(C1=CC=C(C2=CSC=C2)C(NC(NC3=CC=CC(C(F)(F)F)=C3)=O)=C1)(NC4CC4)=O
  • Chemical Name
    N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang F, et al. Science. 2013 May 3;340(6132):622-6.
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