euphol

CAS No. 514-47-6

euphol( —— )

Catalog No. M20457 CAS No. 514-47-6

Euphol an alcohol tetracyclic triterpene has a wide range of pharmacological properties and is considered to have anti-inflammatory action.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 178 In Stock
10MG 312 In Stock
25MG 563 In Stock
50MG 799 In Stock
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Biological Information

  • Product Name
    euphol
  • Note
    Research use only, not for human use.
  • Brief Description
    Euphol an alcohol tetracyclic triterpene has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
  • Description
    Euphol an alcohol tetracyclic triterpene has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
  • In Vitro
    Euphol (0.01-0.3 mM; 24-72 hours) markedly inhibits T47D cells proliferation, the IC50 values of euphol treatment for 24, 48 and 72 h were 0.26, 0.22 and 0.13 mM, respectively.Euphol (0.03 mM; 48 or 72 hours) leads to cell cycle arrest by regulating expression of cell cycle-associated proteins. Cell Proliferation Assay Cell Line:T47D cells Concentration:0.01, 0.03, 0.1 and 0.3 mM Incubation Time:24, 48 and 72 hours Result:Decreased the percentage of viable cells.Western Blot Analysis Cell Line:T47D cells Concentration:0.03 mM Incubation Time:48 and 72 hours Result:Increased the expression of p21 and p27, reduced the expression of cyclin A, B1 and D.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    514-47-6
  • Formula Weight
    426.7
  • Molecular Formula
    C30H50O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (58.59 mM)
  • SMILES
    [H][C@]1(CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CC\C=C(/C)C
  • Chemical Name
    (3S5R10R13R14S17R)-44101314-pentamethyl-17-((R)-6-methylhept-5-en-2-yl)-2345671011121314151617-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dutra R C Bento A F Marcon R et al. Euphol a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system[J]. Neuropharmacology 2012 63(4):593-605.
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