Cart
sales@molnova.com
Pronetalol
CAS No. 54-80-8
Pronetalol( —— )
Catalog No. M33103 CAS No. 54-80-8
Pronethalol ((±)-Pronethalol), a non-selective β-adrenergic antagonist, effectively inhibits Sox2 expression and offers protection against Digitalis-induced ventricular arrhythmias.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
|
| 5MG | 39 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePronetalol
-
NoteResearch use only, not for human use.
-
Brief DescriptionPronethalol ((±)-Pronethalol), a non-selective β-adrenergic antagonist, effectively inhibits Sox2 expression and offers protection against Digitalis-induced ventricular arrhythmias.
-
DescriptionPronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias and limits the cerebral arteriovenous malformation (AVMs).
-
In VitroPronethalol (2, 10, 20 μM) represses EGFP expression in a dose- and time-dependent manner in ReNcell VM cells. Pronethalol (10 μM; 2 days) reduces Sox2 expression to less than 10% after 2 days of treatment.
-
In VivoPronethalol (0.15 mg/g; daily; for 14 days) stabilizes endothelial differentiation, lumen formation and improves cerebral arteriovenous malformation (AVMs) in Mgp–/– mice.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number54-80-8
-
Formula Weight229.32
-
Molecular FormulaC15H19NO
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (218.04 mM; Ultrasonic )
-
SMILESCC(C)NCC(O)c1ccc2ccccc2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Aroesty JM, et al. The effects of a beta-adrenergic blocking agent, pronethalol, on digitalis-induced ventricular arrhythmias. Am Heart J. 1966 Apr;71(4):503-8.?
molnova catalog
related products
-
7,12-DIMETHYLBENZ[A]...
7,12-Dimethylbenz[a]anthracene is a highly potent carcinogen that is activated by microsomal enzymes to a diol epoxide metabolite that binds covalently to DNA in mammalian cells, leading ultimately to tumor induction.
-
Melitidin
Melitidin was discovered in bergamot orange juice and exhibits statin-like properties,so the juice seems to have hypolipidemic activity.
-
Aristola-1(10),8-die...
Aristola-1(10),8-dien-2-one is a natural product. Aristola-1(10),8-dien-2-one can be used as a reference standard.
